Living evidence for real decisionsEvidence you can actually trust.
Refine.med turns complex research into clear treatment guidance for clinicians, patients, and families. One place for reliable evidence, starting with Huntington's disease.
Condition coverage
Where evidence is live today and what lands next.
Huntington's disease
LiveFull guidance with weekly change notes.
ALS
In reviewEvidence map in curation.
Parkinson's disease
Next upFramework ready; layering studies next.
Latest change note
2 days agoMonitoring guidance refreshed for tetrabenazine dosing and mood tracking.
See how we update guidanceWhere to start
Start with Huntington's disease; ALS and Parkinson's updates follow soon.
Pick the path that fits you
Clear routes for every visitor
Use the hero buttons to jump into the path that fits you. Here's what each view gives you once you're inside. You'll start on Huntington's disease; more conditions are coming.
Clinicians
Fast, evidence-weighted guidance to support point-of-care decisions.
What you'll find
- Point-of-care pathways with caveats kept in view.
- Effect sizes, monitoring notes, and safety watchouts.
- Printable context you can share with patients and families.
You'll start on Huntington's disease; more conditions soon.
People living with a condition
Plain-language explanations, what to expect, and questions to ask your team.
What you'll find
- Plain-language guides to treatments and side effects.
- What to expect across stages, with safety notes called out.
- Questions to bring to your next appointment.
You'll start on Huntington's disease; more conditions soon.
Carers & families
Practical support, safety notes, and ways to participate in shared decisions.
What you'll find
- How to support shared decisions and monitor changes.
- Safety guidance for the home and day-to-day routines.
- Ways to participate in clinic visits without losing nuance.
You'll start on Huntington's disease; more conditions soon.
Conditions we cover
Starting with Huntington's disease
A growing platform for neurodegenerative conditions. Today, you can explore our full Huntington's disease guidance with the same patterns we'll reuse as more conditions arrive.
Huntington's disease
Evidence-based treatment guidance, updated as new data emerges. Built with clinicians, patients, and families so the nuance stays intact.
Next conditions in the queue
We're expanding to other neurodegenerative conditions. Start with Huntington's disease and tell us which condition to prioritize next.
ALS
Evidence map in review.
Parkinson's disease
Framework built; layering studies next.
Want updates? hello@refine.med.
How Refine.med works
Evidence with context, not headlines
Built to be skimmed at the point of care but detailed enough to see trade-offs. Here's the short version of our approach.
Step 1
Scan the evidence
Registered trials, living reviews, and real-world signals stay on our radar.
Step 2
Map treatments to outcomes
Benefits, harms, and monitoring notes connect to outcomes that matter to people.
Step 3
Translate into guidance
Condition-specific explanations with plain language, effect sizes, and caveats.
Step 4
Keep it current
Versioned updates with change notes as new trials land or evidence shifts.
Why you can trust this
Accuracy, methods, and privacy in one place
We blend rigorous evidence methods with privacy that treats health content as sensitive by default.
Accuracy & methods
High-quality evidence, explained with nuance
- Sources include registered trials, systematic reviews, and major observational cohorts.
- Plain-language summaries keep caveats intact, not just headline outcomes.
- Expert oversight and transparent change logs show when guidance shifts.
Privacy & safety
Mental health stays on the page
- No remarketing or behavioural tracking on sensitive journeys.
- Data stays on the page; we do not share with advertisers.
- Clear safety guidance for mental health content.
We keep tracking minimal, avoid remarketing pixels, and write explicitly about how to seek support.